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Coding transcriptome analyses reveal altered functions underlying immunotolerance of PEG-fused rat sciatic nerve allografts

BACKGROUND: Current methods to repair ablation-type peripheral nerve injuries (PNIs) using peripheral nerve allografts (PNAs) often result in poor functional recovery due to immunological rejection as well as to slow and inaccurate outgrowth of regenerating axonal sprouts. In contrast, ablation-type...

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Detalles Bibliográficos
Autores principales: Smith, Tyler A., Ghergherehchi, Cameron L., Tucker, Haley O., Bittner, George D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532577/
https://www.ncbi.nlm.nih.gov/pubmed/33008419
http://dx.doi.org/10.1186/s12974-020-01953-8