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Kojic acid repurposing as a pancreatic lipase inhibitor and the optimization of its production from a local Aspergillus oryzae soil isolate

BACKGROUND: Obesity and its related diseases are increasing worldwide. One of the best therapeutic strategies for obesity management is through the inhibition of pancreatic lipase (PL) enzyme. So far orlistat is the only FDA approved PL inhibitor, but with unpleasant side effects. New efficacious an...

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Detalles Bibliográficos
Autores principales: El-Korany, Sarah Mohamed, Helmy, Omneya Mohamed, El-Halawany, Ali Mahmoud, Ragab, Yasser El-Mohammadi, Zedan, Hamdallah Hafez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532584/
https://www.ncbi.nlm.nih.gov/pubmed/33008398
http://dx.doi.org/10.1186/s12896-020-00644-9