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Kojic acid repurposing as a pancreatic lipase inhibitor and the optimization of its production from a local Aspergillus oryzae soil isolate
BACKGROUND: Obesity and its related diseases are increasing worldwide. One of the best therapeutic strategies for obesity management is through the inhibition of pancreatic lipase (PL) enzyme. So far orlistat is the only FDA approved PL inhibitor, but with unpleasant side effects. New efficacious an...
Autores principales: | El-Korany, Sarah Mohamed, Helmy, Omneya Mohamed, El-Halawany, Ali Mahmoud, Ragab, Yasser El-Mohammadi, Zedan, Hamdallah Hafez |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532584/ https://www.ncbi.nlm.nih.gov/pubmed/33008398 http://dx.doi.org/10.1186/s12896-020-00644-9 |
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