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Generation of cortical neurons through large-scale expanding neuroepithelial stem cell from human pluripotent stem cells

BACKGROUND: Considerable progress has been made in converting human pluripotent stem cells (hPSCs) into cortical neurons for disease modeling and regenerative medicine. However, these procedures are hard to provide sufficient cells for their applications. Using a combination of small-molecules and g...

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Detalles Bibliográficos
Autores principales: Zhao, Shumei, Duan, Kui, Ai, Zongyong, Niu, Baohua, Chen, Yanying, Kong, Ruize, Li, Tianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532602/
https://www.ncbi.nlm.nih.gov/pubmed/33008480
http://dx.doi.org/10.1186/s13287-020-01939-6