Intracellular calcium current disorder and disease phenotype in OBSCN mutant iPSC-based cardiomyocytes in arrhythmogenic right ventricular cardiomyopathy

Obscurin participates in the development of striated muscles and maintenance of the functional sarcoplasmic reticulum. However, the role of obscurin in arrhythmogenic right ventricular cardiomyopathy (ARVC) is not well understood. We aimed to study the novel obscurin mutations in the pathogenesis of...

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Detalles Bibliográficos
Autores principales: Chen, Peipei, Xiao, Ying, Wang, Yuanpin, Zheng, Zhifa, Chen, Lianfeng, Yang, Xufei, Li, Jingyi, Wu, Wei, Zhang, Shuyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532677/
https://www.ncbi.nlm.nih.gov/pubmed/33042279
http://dx.doi.org/10.7150/thno.45172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532677/
https://www.ncbi.nlm.nih.gov/pubmed/33042279
http://dx.doi.org/10.7150/thno.45172

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