Truncated HDAC9 identified by integrated genome-wide screen as the key modulator for paclitaxel resistance in triple-negative breast cancer

Rationale: Paclitaxel resistance is a major concern when treating triple-negative breast cancer (TNBC) patients. We aimed to identify candidates causing paclitaxel resistance and explore their significance in TNBC therapeutics. Methods: A genome-wide CRISPR screening, integrated with transcriptome a...

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Detalles Bibliográficos
Autores principales: Lian, Bi, Pei, Yu-Chen, Jiang, Yi-Zhou, Xue, Meng-Zhu, Li, Da-Qiang, Li, Xiao-Guang, Zheng, Yi-Zi, Liu, Xi-Yu, Qiao, Feng, Sun, Wei-Li, Ling, Hong, He, Min, Yao, Ling, Hu, Xin, Shao, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532680/
https://www.ncbi.nlm.nih.gov/pubmed/33042272
http://dx.doi.org/10.7150/thno.44997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532680/
https://www.ncbi.nlm.nih.gov/pubmed/33042272
http://dx.doi.org/10.7150/thno.44997

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