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Vaccines based on replication incompetent Ad26 viral vectors: Standardized template with key considerations for a risk/benefit assessment()

Replication-incompetent adenoviral vectors have been under investigation as a platform to carry a variety of transgenes, and express them as a basis for vaccine development. A replication-incompetent adenoviral vector based on human adenovirus type 26 (Ad26) has been evaluated in several clinical tr...

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Detalles Bibliográficos
Autores principales: Custers, Jerome, Kim, Denny, Leyssen, Maarten, Gurwith, Marc, Tomaka, Frank, Robertson, James, Heijnen, Esther, Condit, Richard, Shukarev, Georgi, Heerwegh, Dirk, van Heesbeen, Roy, Schuitemaker, Hanneke, Douoguih, Macaya, Evans, Eric, Smith, Emily R., Chen, Robert T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532807/
https://www.ncbi.nlm.nih.gov/pubmed/33676782
http://dx.doi.org/10.1016/j.vaccine.2020.09.018