Investigation of the Effect of 5-Aza-2ʹ-Deoxycytidine on p15INK4, p16INK4, p18INK4, and p19INK4 Genes Expression, Cell Growth Inhibition, and Apoptosis Induction in Hepatocellular Carcinoma PLC/PRF/5 Cell Line

BACKGROUND: Cyclin-dependent kinases (CDKs) are the key regulators of cell-cycle transitions and characterized by needing a separate subunit, a cyclin, which provides domains essential for enzymatic activity. The activities of cyclin-CDK complexes are controlled by a group of molecules that inhibit...

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Detalles Bibliográficos
Autores principales: Sanaei, Masumeh, Kavoosi, Fraidoon, Ghasemi, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532824/
https://www.ncbi.nlm.nih.gov/pubmed/33072645
http://dx.doi.org/10.4103/abr.abr_68_20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532824/
https://www.ncbi.nlm.nih.gov/pubmed/33072645
http://dx.doi.org/10.4103/abr.abr_68_20

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