DNA-PK: gatekeeper for IKKγ/NEMO nucleocytoplasmic shuttling in genotoxic stress-induced NF-kappaB activation

The transcription factors of the nuclear factor κB (NF-κB) family play a pivotal role in the cellular response to DNA damage. Genotoxic stress-induced activation of NF-κB differs from the classical canonical pathway by shuttling of the NF-κB Essential Modifier (IKKγ/NEMO) subunit through the nucleus...

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Detalles Bibliográficos
Autores principales: Medunjanin, Senad, Putzier, Maximilian, Nöthen, Till, Weinert, Sönke, Kähne, Thilo, Luani, Blerim, Zuschratter, Werner, Braun-Dullaeus, Ruediger C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532968/
https://www.ncbi.nlm.nih.gov/pubmed/31932854
http://dx.doi.org/10.1007/s00018-019-03411-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532968/
https://www.ncbi.nlm.nih.gov/pubmed/31932854
http://dx.doi.org/10.1007/s00018-019-03411-y

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