EZH2-dependent epigenetic modulation of histone H3 lysine-27 contributes to psoriasis by promoting keratinocyte proliferation

Psoriasis is characterized by keratinocyte hyperproliferation. While significant progress has been made in understanding the molecular mechanism regulating the proliferation of keratinocytes, little is known about the epigenetic factors that control this process. EZH2 and EZH2 mediated trimethylatio...

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Detalles Bibliográficos
Autores principales: Zhang, Tongmei, Yang, Luting, Ke, Yao, Lei, Jie, Shen, Shengxian, Shao, Shuai, Zhang, Chen, Zhu, Zhenlai, Dang, Erle, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532974/
https://www.ncbi.nlm.nih.gov/pubmed/33011750
http://dx.doi.org/10.1038/s41419-020-03028-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532974/
https://www.ncbi.nlm.nih.gov/pubmed/33011750
http://dx.doi.org/10.1038/s41419-020-03028-1

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