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B7-H3 regulates KIF15-activated ERK1/2 pathway and contributes to radioresistance in colorectal cancer

As an important modality for the local control of colorectal cancer (CRC), radiotherapy or neoadjuvant radiotherapy is widely applied in the clinic, but radioresistance has become a major obstacle for CRC radiotherapy. Here we reported that B7-H3, an important costimulatory molecule, is associated w...

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Detalles Bibliográficos
Autores principales: Ma, Yanchao, Zhan, Shenghua, Lu, Huimin, Wang, Ruoqin, Xu, Yunyun, Zhang, Guangbo, Cao, Lei, Shi, Tongguo, Zhang, Xueguang, Chen, Weichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7532977/
https://www.ncbi.nlm.nih.gov/pubmed/33011740
http://dx.doi.org/10.1038/s41419-020-03041-4