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Elucidating the Pivotal Immunomodulatory and Anti-Inflammatory Potentials of Chloroquine and Hydroxychloroquine

Chloroquine (CQ) and hydroxychloroquine (HCQ) are derivatives of 4-aminoquinoline compounds with over 60 years of safe clinical usage. CQ and HCQ are able to inhibit the production of cytokines such as interleukin- (IL-) 1, IL-2, IL-6, IL-17, and IL-22. Also, CQ and HCQ inhibit the production of int...

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Detalles Bibliográficos
Autores principales: Richard, Seidu A., Kampo, Sylvanus, Hechavarria, Maite Esquijarosa, Sackey, Marian, Buunaaim, Alexis D. B., Kuugbee, Eugene Dogkotenge, Anabah, Thomas Winsum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533005/
https://www.ncbi.nlm.nih.gov/pubmed/33062720
http://dx.doi.org/10.1155/2020/4582612