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NRXN1 as a novel potential target of antibody-drug conjugates for small cell lung cancer

Small cell lung cancer (SCLC) is a high-grade malignancy, and treatment strategies have not changed for decades. In this study, we searched for novel targets for antibody-drug conjugate (ADC) therapy for SCLC. We identified transmembrane proteins overexpressed specifically in SCLC with little or no...

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Detalles Bibliográficos
Autores principales: Yotsumoto, Takuma, Maemura, Keita, Watanabe, Kousuke, Amano, Yosuke, Matsumoto, Yoko, Zokumasu, Koichi, Ando, Takahiro, Kawakami, Masanori, Kage, Hidenori, Nakajima, Jun, Yatomi, Yutaka, Nagase, Takahide, Takai, Daiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533074/
https://www.ncbi.nlm.nih.gov/pubmed/33062195
http://dx.doi.org/10.18632/oncotarget.27718