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Antiallodynic and anti-inflammatory effects of intrathecal R-PIA in a rat model of vincristine-induced peripheral neuropathy

BACKGROUND: Studies investigating the correlation between spinal adenosine A(1) receptors and vincristine-induced peripheral neuropathy (VIPN) are limited. This study explored the role of intrathecal N6-(2-phenylisopropyl)-adenosine R-(-)isomer (R-PIA) in the rat model of VIPN. METHODS: Vincristine...

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Detalles Bibliográficos
Autores principales: Kim, Kyungmi, Jeong, Wonyeong, Jun, In Gu, Park, Jong Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Anesthesiologists 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533172/
https://www.ncbi.nlm.nih.gov/pubmed/32046474
http://dx.doi.org/10.4097/kja.19481