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An Interpretable Prediction Model for Identifying N(7)-Methylguanosine Sites Based on XGBoost and SHAP

Recent studies have increasingly shown that the chemical modification of mRNA plays an important role in the regulation of gene expression. N(7)-methylguanosine (m7G) is a type of positively-charged mRNA modification that plays an essential role for efficient gene expression and cell viability. Howe...

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Detalles Bibliográficos
Autores principales: Bi, Yue, Xiang, Dongxu, Ge, Zongyuan, Li, Fuyi, Jia, Cangzhi, Song, Jiangning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533297/
https://www.ncbi.nlm.nih.gov/pubmed/33230441
http://dx.doi.org/10.1016/j.omtn.2020.08.022