Cargando…

TLR3/TAK1 signalling regulates rhinovirus-induced interleukin-33 in bronchial smooth muscle cells

BACKGROUND: Asthma exacerbations are commonly associated with rhinovirus (RV) infection. Interleukin-33 (IL-33) plays an important role during exacerbation by enhancing Type 2 inflammation. Recently we showed that RV infects bronchial smooth muscle cells (BSMCs) triggering production of interferons...

Descripción completa

Detalles Bibliográficos
Autores principales: Ramu, Sangeetha, Calvén, Jenny, Michaeloudes, Charalambos, Menzel, Mandy, Akbarshahi, Hamid, Chung, Kian Fan, Uller, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533303/
https://www.ncbi.nlm.nih.gov/pubmed/33043044
http://dx.doi.org/10.1183/23120541.00147-2020