Antitumor Activity In Vivo and Vitro of New Chiral Derivatives of Baicalin and Induced Apoptosis via the PI3K/Akt Signaling Pathway

In this study, a pair of chiral baicalin (BA) derivatives were synthesized by combining BA with phenylalanine methyl ester based on molecular docking technology, namely BAD and BAL. Cell cytotoxicity trails showed that the cell growth inhibitory effects of both BAD and BAL were increased by 8- to 12...

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Detalles Bibliográficos
Autores principales: Hou, Yi, Pi, Chao, Feng, Xianhu, Wang, Yuanyuan, Fu, Shaozhi, Zhang, Xiaomei, Zhao, Ling, Wei, Yumeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533372/
https://www.ncbi.nlm.nih.gov/pubmed/33072864
http://dx.doi.org/10.1016/j.omto.2020.08.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533372/
https://www.ncbi.nlm.nih.gov/pubmed/33072864
http://dx.doi.org/10.1016/j.omto.2020.08.018

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