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Emerging insights on the role of gasdermins in infection and inflammatory diseases

The gasdermins, family of pore‐forming proteins, are emerging key regulators of infection, autoinflammation and antitumor immunity. Multiple studies have recently characterised their crucial roles in driving pyroptosis, a lytic pro‐inflammatory type of cell death. Additionally, gasdermins also act a...

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Detalles Bibliográficos
Autores principales: Tang, Lipeng, Lu, Chuanjian, Zheng, Guangjuan, Burgering, Boudewijn MT
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533414/
https://www.ncbi.nlm.nih.gov/pubmed/33033617
http://dx.doi.org/10.1002/cti2.1186