Protective effects of valsartan administration on doxorubicin-induced myocardial injury in rats and the role of oxidative stress and NOX2/NOX4 signaling

Clinical application of doxorubicin (DOX) is hampered by its potential cardiotoxicity, however angiotensin receptor blockers could attenuate DOX-induced cardiomyopathy. The present study tested the hypothesis that simultaneous administration of valsartan (Val) with DOX could prevent DOX-induced myoc...

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Detalles Bibliográficos
Autores principales: Cheng, Dong, Chen, Libo, Tu, Wencheng, Wang, Haoren, Wang, Qinfu, Meng, Lili, Li, Zhu, Yu, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533445/
https://www.ncbi.nlm.nih.gov/pubmed/33000246
http://dx.doi.org/10.3892/mmr.2020.11521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533445/
https://www.ncbi.nlm.nih.gov/pubmed/33000246
http://dx.doi.org/10.3892/mmr.2020.11521

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