SDF1/CXCR4 axis facilitates the angiogenesis via activating the PI3K/AKT pathway in degenerated discs

Symptomatic degenerative disc disease (DDD) is considered the leading cause of chronic lower back pain (LBP). As one of the main features of intervertebral disc degeneration (IDD), vascular ingrowth plays a crucial role in the progression of LBP. Stromal cell-derived factor 1 (SDF1) and its receptor...

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Detalles Bibliográficos
Autores principales: Zhang, Hanxiang, Wang, Peng, Zhang, Xiang, Zhao, Wenrui, Ren, Honglei, Hu, Zhenming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533460/
https://www.ncbi.nlm.nih.gov/pubmed/32901877
http://dx.doi.org/10.3892/mmr.2020.11498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533460/
https://www.ncbi.nlm.nih.gov/pubmed/32901877
http://dx.doi.org/10.3892/mmr.2020.11498

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