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Icariin modulates the sirtuin/NF-κB pathway and exerts anti-aging effects in human lung fibroblasts

Icariin (ICA) has been used as a promising anti-aging drug; however, its underlying molecular mechanism is yet to be elucidated. The present study aimed to determine the anti-aging molecular mechanisms of ICA. D-galactose (D-gal) was used to generate a cell aging model. IMR-90 human lung fibroblasts...

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Detalles Bibliográficos
Autores principales: Xu, Changqing, Huang, Xuqing, Tong, Yueyang, Feng, Xiaocheng, Wang, Yan, Wang, Cancan, Jiang, Yuyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533484/
https://www.ncbi.nlm.nih.gov/pubmed/33000191
http://dx.doi.org/10.3892/mmr.2020.11458