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Cancer stem cells as a therapeutic target in 3D tumor models of human chondrosarcoma: An encouraging future for proline rich polypeptide-1

Chondrosarcoma is a malignant bone neoplasm that is refractory to chemotherapy and radiation. With no current biological treatments, mutilating surgical resection is the only effective treatment. Proline rich polypeptide 1 (PRP-1), which is a 15-amino acid inhibitor of mammalian target of rapamycin...

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Detalles Bibliográficos
Autores principales: Granger, Caroline J., Hoyt, Aaron K., Moran, Alexandra, Becker, Beatrice, Sedani, Anil, Saigh, Shannon, Conway, Sheila A., Brown, Jeffrey, Galoian, Karina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533489/
https://www.ncbi.nlm.nih.gov/pubmed/32901865
http://dx.doi.org/10.3892/mmr.2020.11480