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Cancer stem cells as a therapeutic target in 3D tumor models of human chondrosarcoma: An encouraging future for proline rich polypeptide-1
Chondrosarcoma is a malignant bone neoplasm that is refractory to chemotherapy and radiation. With no current biological treatments, mutilating surgical resection is the only effective treatment. Proline rich polypeptide 1 (PRP-1), which is a 15-amino acid inhibitor of mammalian target of rapamycin...
Autores principales: | Granger, Caroline J., Hoyt, Aaron K., Moran, Alexandra, Becker, Beatrice, Sedani, Anil, Saigh, Shannon, Conway, Sheila A., Brown, Jeffrey, Galoian, Karina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533489/ https://www.ncbi.nlm.nih.gov/pubmed/32901865 http://dx.doi.org/10.3892/mmr.2020.11480 |
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