The AKT inhibitor MK2206 suppresses airway inflammation and the pro-remodeling pathway in a TDI-induced asthma mouse model

The cellular and molecular mechanisms via which MK2206, an AKT inhibitor, prevents the activation of AKT in toluene diisocyanate (TDI)-induced asthma remain unclear. Thus, the present study aimed to evaluate the potential effects of MK2206 on airway AKT activation, inflammation and remodeling in a T...

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Detalles Bibliográficos
Autores principales: Cui, Haiyan, Cheng, Yuanxiong, He, Yi, Cheng, Weiying, Zhao, Wenqu, Zhao, Haijin, Zhou, Fiona H., Wang, Liping, Dong, Jianghui, Cai, Shaoxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533517/
https://www.ncbi.nlm.nih.gov/pubmed/33000187
http://dx.doi.org/10.3892/mmr.2020.11450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533517/
https://www.ncbi.nlm.nih.gov/pubmed/33000187
http://dx.doi.org/10.3892/mmr.2020.11450

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