Effects of PEG anchors in PEGylated siRNA lipoplexes on in vitro gene-silencing effects and siRNA biodistribution in mice

Polyethylene glycol (PEG)-modifications (PEGylations) of cationic liposome/small interfering RNA complexes (siRNA lipoplexes) can enhance their systemic stability. The present study determined the effects of PEG anchors in PEGylated siRNA lipoplexes on in vitro gene-silencing effects and siRNA biodi...

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Detalles Bibliográficos
Autores principales: Hattori, Yoshiyuki, Tamaki, Kyoko, Sakasai, Sho, Ozaki, Kei-Ichi, Onishi, Hiraku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533518/
https://www.ncbi.nlm.nih.gov/pubmed/33000194
http://dx.doi.org/10.3892/mmr.2020.11525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533518/
https://www.ncbi.nlm.nih.gov/pubmed/33000194
http://dx.doi.org/10.3892/mmr.2020.11525

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