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Molecular Insights Into Regulatory T-Cell Adaptation to Self, Environment, and Host Tissues: Plasticity or Loss of Function in Autoimmune Disease

There has been much interest in the ability of regulatory T cells (Treg) to switch function in vivo, either as a result of genetic risk of disease or in response to environmental and metabolic cues. The relationship between levels of FOXP3 and functional fitness plays a significant part in this plas...

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Detalles Bibliográficos
Autores principales: Brown, Cheryl Y., Sadlon, Timothy, Hope, Christopher M., Wong, Ying Y., Wong, Soon, Liu, Ning, Withers, Holly, Brown, Katherine, Bandara, Veronika, Gundsambuu, Batjargal, Pederson, Stephen, Breen, James, Robertson, Sarah Anne, Forrest, Alistair, Beyer, Marc, Barry, Simon Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533603/
https://www.ncbi.nlm.nih.gov/pubmed/33072063
http://dx.doi.org/10.3389/fimmu.2020.01269