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Causal inference in genetic trio studies

We introduce a method to draw causal inferences—inferences immune to all possible confounding—from genetic data that include parents and offspring. Causal conclusions are possible with these data because the natural randomness in meiosis can be viewed as a high-dimensional randomized experiment. We...

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Detalles Bibliográficos
Autores principales: Bates, Stephen, Sesia, Matteo, Sabatti, Chiara, Candès, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533659/
https://www.ncbi.nlm.nih.gov/pubmed/32948695
http://dx.doi.org/10.1073/pnas.2007743117