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General and robust covalently linked graphene oxide affinity grids for high-resolution cryo-EM

Affinity grids have great potential to facilitate rapid preparation of even quite impure samples in single-particle cryo-electron microscopy (EM). Yet despite the promising advances of affinity grids over the past decades, no single strategy has demonstrated general utility. Here we chemically funct...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Liu, Yanxin, Yu, Zanlin, Li, Sam, Feng, Shengjie, Cheng, Yifan, Agard, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533693/
https://www.ncbi.nlm.nih.gov/pubmed/32913054
http://dx.doi.org/10.1073/pnas.2009707117