The Metalloproteinase ADAMTS5 Is Expressed by Interstitial Inflammatory Cells in IgA Nephropathy and Is Proteolytically Active on the Kidney Matrix

In IgA nephropathy (IgAN), IgA immune complexes are deposited in the mesangium and drive inflammation and extracellular matrix (ECM) remodelling. The functional links between IgA deposition, inflammation, and matrix remodelling are not well characterized. We recently performed urine liquid chromatog...

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Detalles Bibliográficos
Autores principales: Taylor, Scott, Whitfield, Molly, Barratt, Jonathan, Didangelos, Athanasios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2020
Materias:
Innate Immunity and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533710/
https://www.ncbi.nlm.nih.gov/pubmed/32917786
http://dx.doi.org/10.4049/jimmunol.2000448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533710/
https://www.ncbi.nlm.nih.gov/pubmed/32917786
http://dx.doi.org/10.4049/jimmunol.2000448

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