Jmjd3 Plays Pivotal Roles in the Proper Development of Early-Born Retinal Lineages: Amacrine, Horizontal, and Retinal Ganglion Cells

PURPOSE: Trimethylation of histone H3 at lysine 27 (H3K27me3) is a critical mediator of transcriptional gene repression, and Jmjd3 and Utx are the demethylases specific to H3K27me3. Using an in vitro retinal explant culture system, we previously revealed the role of Jmjd3 in the development of rod b...

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Detalles Bibliográficos
Autores principales: Iwagawa, Toshiro, Honda, Hiroaki, Watanabe, Sumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533738/
https://www.ncbi.nlm.nih.gov/pubmed/32986815
http://dx.doi.org/10.1167/iovs.61.11.43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533738/
https://www.ncbi.nlm.nih.gov/pubmed/32986815
http://dx.doi.org/10.1167/iovs.61.11.43

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