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Regulation of titin-based cardiac stiffness by unfolded domain oxidation (UnDOx)
The relationship between oxidative stress and cardiac stiffness is thought to involve modifications to the giant muscle protein titin, which in turn can determine the progression of heart disease. In vitro studies have shown that S-glutathionylation and disulfide bonding of titin fragments could alt...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533878/ https://www.ncbi.nlm.nih.gov/pubmed/32929035 http://dx.doi.org/10.1073/pnas.2004900117 |