Regulation of titin-based cardiac stiffness by unfolded domain oxidation (UnDOx)

The relationship between oxidative stress and cardiac stiffness is thought to involve modifications to the giant muscle protein titin, which in turn can determine the progression of heart disease. In vitro studies have shown that S-glutathionylation and disulfide bonding of titin fragments could alt...

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Detalles Bibliográficos
Autores principales: Loescher, Christine M., Breitkreuz, Martin, Li, Yong, Nickel, Alexander, Unger, Andreas, Dietl, Alexander, Schmidt, Andreas, Mohamed, Belal A., Kötter, Sebastian, Schmitt, Joachim P., Krüger, Marcus, Krüger, Martina, Toischer, Karl, Maack, Christoph, Leichert, Lars I., Hamdani, Nazha, Linke, Wolfgang A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533878/
https://www.ncbi.nlm.nih.gov/pubmed/32929035
http://dx.doi.org/10.1073/pnas.2004900117

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