Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis via modulating protein stability of β-catenin and β-catenin-mediated transcription

BACKGROUND: Renal fibrosis is the common feature of chronic kidney disease (CKD). However, few drugs specifically target fibrogenesis due to the lack of an effective therapeutic target. Hence, it is urgent to find a therapeutic strategy that inhibits renal fibrosis. Here, we identified that poricoic...

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Detalles Bibliográficos
Autores principales: Chen, Dan-Qian, Wu, Xia-Qing, Chen, Lin, Hu, He-He, Wang, Yan-Ni, Zhao, Ying-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534062/
https://www.ncbi.nlm.nih.gov/pubmed/33062239
http://dx.doi.org/10.1177/2040622320962648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534062/
https://www.ncbi.nlm.nih.gov/pubmed/33062239
http://dx.doi.org/10.1177/2040622320962648

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