The structural basis for the selectivity of sulfonamido dicarbaboranes toward cancer-associated carbonic anhydrase IX

Human carbonic anhydrase IX (CA IX), a protein specifically expressed on the surface of solid tumour cells, represents a validated target both for anticancer therapy and diagnostics. We recently identified sulfonamide dicarbaboranes as promising inhibitors of CA IX with favourable activities both in...

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Detalles Bibliográficos
Autores principales: Kugler, Michael, Holub, Josef, Brynda, Jiří, Pospíšilová, Klára, Anwar, Suzan El, Bavol, Dmytro, Havránek, Miroslav, Král, Vlastimil, Fábry, Milan, Grüner, Bohumír, Řezáčová, Pavlína
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534198/
https://www.ncbi.nlm.nih.gov/pubmed/32962427
http://dx.doi.org/10.1080/14756366.2020.1816996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534198/
https://www.ncbi.nlm.nih.gov/pubmed/32962427
http://dx.doi.org/10.1080/14756366.2020.1816996

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