Design, synthesis, and evaluation of novel N'-substituted-1-(4-chlorobenzyl)-1H-indol-3-carbohydrazides as antitumor agents

In continuity of our search for novel anticancer agents acting as procaspase activators, we have designed and synthesised two series of (E)-N′-benzylidene-carbohydrazides (4a–m) and (Z)-N'-(2-oxoindolin-3-ylidene)carbohydrazides (5a–g) incorporating 1-(4-chlorobenzyl)-1H-indole core. Bioevaluat...

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Detalles Bibliográficos
Autores principales: Huan, Le Cong, Anh, Duong Tien, Hai, Pham-The, Anh, Lai Duc, Park, Eun Jae, Ji, A Young, Kang, Jong Soon, Dung, Do Thi Mai, Oanh, Dao Thi Kim, Tung, Truong Thanh, Hai, Dinh Thi Thanh, Han, Sang-Bae, Nam, Nguyen-Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534272/
https://www.ncbi.nlm.nih.gov/pubmed/32981382
http://dx.doi.org/10.1080/14756366.2020.1816997

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534272/
https://www.ncbi.nlm.nih.gov/pubmed/32981382
http://dx.doi.org/10.1080/14756366.2020.1816997

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