Toxicity evaluation of sulfamides and coumarins that efficiently inhibit human carbonic anhydrases

Here, we report a toxicity study, conducted on zebrafish larvae, of a series of coumarin and sulfamide compounds that were previously reported as inhibitors of human (h) metalloenzymes, carbonic anhydrases (CAs, EC 4.2.1.1). Due to the high relevance of hCA inhibitors as theragnostic agents, it is o...

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Detalles Bibliográficos
Autores principales: Aspatwar, Ashok, Berrino, Emanuela, Bua, Silvia, Carta, Fabrizio, Capasso, Clemente, Parkkila, Seppo, Supuran, Claudiu T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534274/
https://www.ncbi.nlm.nih.gov/pubmed/32942905
http://dx.doi.org/10.1080/14756366.2020.1822829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534274/
https://www.ncbi.nlm.nih.gov/pubmed/32942905
http://dx.doi.org/10.1080/14756366.2020.1822829

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