Apatinib-loaded CalliSpheres Beads for embolization in a rabbit VX2 liver tumor: characterization in vitro, pharmacokinetics and tumor response in vivo

Apatinib mesylate is an oral antiangiogenic agent that can inhibit activation of vascular endothelial growth factor receptor-2 tyrosine kinase. However, its therapeutic use in liver cancer is restricted due to severe systemic toxicity. Our work aimed to construct apatinib-loaded CalliSpheres Beads (...

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Detalles Bibliográficos
Autores principales: Shi, Qin, Lu, Yongning, Huang, Songjiang, Zhou, Chen, Yang, Chongtu, Liu, Jiacheng, Ma, Jinqiang, Xiong, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534301/
https://www.ncbi.nlm.nih.gov/pubmed/32924634
http://dx.doi.org/10.1080/10717544.2020.1818881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534301/
https://www.ncbi.nlm.nih.gov/pubmed/32924634
http://dx.doi.org/10.1080/10717544.2020.1818881

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