Structure-activity relationship of 7-aryl-2-anilino-pyrrolopyrimidines as Mer and Axl tyrosine kinase inhibitors

The TAM (Axl, Mer, and Tyro3) family is implicated in the survival and chemoresistance of tumours and has emerged as a potential therapeutic target. A novel series of 7-aryl-2-anilino-pyrrolopyrimidines were identified as potent Axl/Mer tyrosine kinase inhibitors without significant inhibition of Ty...

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Detalles Bibliográficos
Autores principales: Chung, Shin Hyuck, Park, Jiwon, Lee, Jung Wuk, Song, Jiho, Jung, Danbee, Min, Kyung Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534383/
https://www.ncbi.nlm.nih.gov/pubmed/32972253
http://dx.doi.org/10.1080/14756366.2020.1825407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534383/
https://www.ncbi.nlm.nih.gov/pubmed/32972253
http://dx.doi.org/10.1080/14756366.2020.1825407

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