DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease

Repair of covalent DNA-protein crosslinks (DPCs) by DNA-dependent proteases has emerged as an essential genome maintenance mechanism required for cellular viability and tumor suppression. However, how proteolysis is restricted to the crosslinked protein while leaving surrounding chromatin proteins u...

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Detalles Bibliográficos
Autores principales: Reinking, Hannah K., Kang, Hyun-Seo, Götz, Maximilian J., Li, Hao-Yi, Kieser, Anja, Zhao, Shubo, Acampora, Aleida C., Weickert, Pedro, Fessler, Evelyn, Jae, Lucas T., Sattler, Michael, Stingele, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534798/
https://www.ncbi.nlm.nih.gov/pubmed/32853547
http://dx.doi.org/10.1016/j.molcel.2020.08.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534798/
https://www.ncbi.nlm.nih.gov/pubmed/32853547
http://dx.doi.org/10.1016/j.molcel.2020.08.003

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