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A Widespread Neurogenic Potential of Neocortical Astrocytes Is Induced by Injury

Parenchymal astrocytes have emerged as a potential reservoir for new neurons in non-neurogenic brain regions. It is currently unclear how astrocyte neurogenesis is controlled molecularly. Here we show that Notch signaling-deficient astrocytes can generate new neurons after injury. Using single-cell...

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Detalles Bibliográficos
Autores principales: Zamboni, Margherita, Llorens-Bobadilla, Enric, Magnusson, Jens Peter, Frisén, Jonas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534841/
https://www.ncbi.nlm.nih.gov/pubmed/32758425
http://dx.doi.org/10.1016/j.stem.2020.07.006