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A Widespread Neurogenic Potential of Neocortical Astrocytes Is Induced by Injury
Parenchymal astrocytes have emerged as a potential reservoir for new neurons in non-neurogenic brain regions. It is currently unclear how astrocyte neurogenesis is controlled molecularly. Here we show that Notch signaling-deficient astrocytes can generate new neurons after injury. Using single-cell...
Autores principales: | Zamboni, Margherita, Llorens-Bobadilla, Enric, Magnusson, Jens Peter, Frisén, Jonas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534841/ https://www.ncbi.nlm.nih.gov/pubmed/32758425 http://dx.doi.org/10.1016/j.stem.2020.07.006 |
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