Structure activity relationship of novel antiviral nucleosides against Enterovirus A71

Various (North)-methanocarba adenosine derivatives, containing rigid bicyclo[3.1.0]hexane ribose substitution, were screened for activity against representative viruses, and inhibition was observed after treatment of Enterovirus A71 with a 2-chloro-N(6)-1-cyclopropyl-2-methylpropan-1-yl derivative (...

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Detalles Bibliográficos
Autores principales: Tosh, Dilip K., Toti, Kiran S., Hurst, Brett L., Julander, Justin G., Jacobson, Kenneth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534897/
https://www.ncbi.nlm.nih.gov/pubmed/33031923
http://dx.doi.org/10.1016/j.bmcl.2020.127599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534897/
https://www.ncbi.nlm.nih.gov/pubmed/33031923
http://dx.doi.org/10.1016/j.bmcl.2020.127599

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