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Structure activity relationship of novel antiviral nucleosides against Enterovirus A71
Various (North)-methanocarba adenosine derivatives, containing rigid bicyclo[3.1.0]hexane ribose substitution, were screened for activity against representative viruses, and inhibition was observed after treatment of Enterovirus A71 with a 2-chloro-N(6)-1-cyclopropyl-2-methylpropan-1-yl derivative (...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7534897/ https://www.ncbi.nlm.nih.gov/pubmed/33031923 http://dx.doi.org/10.1016/j.bmcl.2020.127599 |