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Renoprotective Effect of Formononetin by Suppressing Smad3 Expression in Db/Db Mice

PURPOSE: Glomerular sclerosis and renal interstitial fibrosis are the most important pathologies in the development of kidney damage under diabetic conditions. Smad3 plays antagonistic roles in high glucose-induced renal tubular fibrosis, which is an important treatment target for diabetic nephropat...

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Detalles Bibliográficos
Autores principales: Lv, Jiawei, Zhuang, Kai, Jiang, Xiyu, Huang, Heqing, Quan, Shijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535125/
https://www.ncbi.nlm.nih.gov/pubmed/33061493
http://dx.doi.org/10.2147/DMSO.S272147