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A case report of neurological adverse events caused by short-term and low-dose treatment of mitotane: The role of therapeutic drug monitoring

RATIONALE: Low-dose mitotane has been widely used for many decades in patients with advanced adrenocortical carcinoma (ACC), which exhibited good safety profiles compared with the high-dose regimen. The clinical efficacy and toxicity of mitotane are closely related to its plasma concentration, and t...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Fu, Qiang, Tang, Yan, Deng, Jian-hua, Mei, Dan, Zhang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535773/
https://www.ncbi.nlm.nih.gov/pubmed/33019484
http://dx.doi.org/10.1097/MD.0000000000022620