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Uncovering a novel molecular mechanism for scavenging sialic acids in bacteria

The human gut symbiont Ruminococcus gnavus scavenges host-derived N-acetylneuraminic acid (Neu5Ac) from mucins by converting it to 2,7-anhydro-Neu5Ac. We previously showed that 2,7-anhydro-Neu5Ac is transported into R. gnavus ATCC 29149 before being converted back to Neu5Ac for further metabolic pro...

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Detalles Bibliográficos
Autores principales: Bell, Andrew, Severi, Emmanuele, Lee, Micah, Monaco, Serena, Latousakis, Dimitrios, Angulo, Jesus, Thomas, Gavin H., Naismith, James H., Juge, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7535918/
https://www.ncbi.nlm.nih.gov/pubmed/32669363
http://dx.doi.org/10.1074/jbc.RA120.014454