Direct comparison of two extended half-life PEGylated recombinant FVIII products: a randomized, crossover pharmacokinetic study in patients with severe hemophilia A

An open-label, crossover randomized study was performed to compare the pharmacokinetics (PK) of damoctocog alfa pegol and rurioctocog alfa pegol, two recombinant factor VIII (FVIII) products indicated in patients with hemophilia A, both conjugated to polyethylene glycol to reduce clearance and exten...

Descripción completa

Detalles Bibliográficos
Autores principales: Solms, Alexander, Shah, Anita, Berntorp, Erik, Tiede, Andreas, Iorio, Alfonso, Linardi, Camila, Ahsman, Maurice, Mancuso, Maria Elisa, Zhivkov, Tihomir, Lissitchkov, Toshko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536163/
https://www.ncbi.nlm.nih.gov/pubmed/32974838
http://dx.doi.org/10.1007/s00277-020-04280-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536163/
https://www.ncbi.nlm.nih.gov/pubmed/32974838
http://dx.doi.org/10.1007/s00277-020-04280-3

Ejemplares similares