Non-hematopoietic deficiency of proprotein convertase subtilisin/kexin type 9 deficiency leads to more severe anemia in a murine model of sickle cell disease

Proprotein convertase subtilisin/kexin type 9 (PCSK9) deficiency leads to lower cholesterol and is associated with reduced vascular complications in the general population. Cholesterol lowering may also have beneficial effects in sickle cell disease (SCD). The objective of this study was to determin...

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Detalles Bibliográficos
Autores principales: Venugopal, J., Wang, J., Guo, C., Lu, H., Chen, Y. E., Eitzman, D. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536178/
https://www.ncbi.nlm.nih.gov/pubmed/33020528
http://dx.doi.org/10.1038/s41598-020-73463-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536178/
https://www.ncbi.nlm.nih.gov/pubmed/33020528
http://dx.doi.org/10.1038/s41598-020-73463-9

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