Allosteric regulation of glutamate dehydrogenase deamination activity

Glutamate dehydrogenase (GDH) is a key enzyme interlinking carbon and nitrogen metabolism. Recent discoveries of the GDH specific role in breast cancer, hyperinsulinism/hyperammonemia (HI/HA) syndrome, and neurodegenerative diseases have reinvigorated interest on GDH regulation, which remains poorly...

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Detalles Bibliográficos
Autores principales: Bera, Soumen, Rashid, Mubasher, Medvinsky, Alexander B., Sun, Gui-Quan, Li, Bai-Lian, Acquisti, Claudia, Sljoka, Adnan, Chakraborty, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536180/
https://www.ncbi.nlm.nih.gov/pubmed/33020580
http://dx.doi.org/10.1038/s41598-020-73743-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536180/
https://www.ncbi.nlm.nih.gov/pubmed/33020580
http://dx.doi.org/10.1038/s41598-020-73743-4

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