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Allosteric regulation of glutamate dehydrogenase deamination activity
Glutamate dehydrogenase (GDH) is a key enzyme interlinking carbon and nitrogen metabolism. Recent discoveries of the GDH specific role in breast cancer, hyperinsulinism/hyperammonemia (HI/HA) syndrome, and neurodegenerative diseases have reinvigorated interest on GDH regulation, which remains poorly...
Autores principales: | Bera, Soumen, Rashid, Mubasher, Medvinsky, Alexander B., Sun, Gui-Quan, Li, Bai-Lian, Acquisti, Claudia, Sljoka, Adnan, Chakraborty, Amit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7536180/ https://www.ncbi.nlm.nih.gov/pubmed/33020580 http://dx.doi.org/10.1038/s41598-020-73743-4 |
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